Biotechnology - Comparable Transaction Analysis


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Announed Date Target/Issuer Transaction Type Buyer/Investor Txn Value Implied TEV
- Imclone Systems Inc. Merger/Acquisition Bristol-Myers Squibb Co. 4,929 4,857
- Biogen Idec Inc. Shelf Registration - - -
7/22/2008 Arius Research Inc. Merger/Acquisition Roche Holding AG 181 172
7/22/2008 Mirus Bio Corporation Merger/Acquisition Roche Holding AG 125 125
- Genentech Inc. Merger/Acquisition Roche Holdings, Inc. 43,638 93,891
7/3/2008 Cellectis Private Placement Regeneron Pharmaceuticals Inc. - -
- Regeneron Pharmaceuticals Inc. Shelf Registration - - -
6/26/2008 ZymoGenetics, Inc. Private Placement Deerfield Management Company L.P. - -
- Affymetrix Inc. Shelf Registration - - -
6/15/2008 Akzo Nobel NV, Para and Crown Diamond Brands in Canada Merger/Acquisition General Paint Corp. - -
- Gilead Sciences Inc. Shelf Registration - - -
6/11/2008 Applera Corp-Applied Biosystems Group (nka:Applied Biosystems Inc.) Merger/Acquisition Invitrogen Corp. 6,523 6,158
- Amylin Pharmaceuticals Inc. Shelf Registration - - -
5/29/2008 Navitas Pharma, Inc. Merger/Acquisition Gilead Sciences Inc. - -
5/27/2008 Amaxa Biosystems GmbH Merger/Acquisition Lonza Group AG - -
5/26/2008 AstraZeneca plc, Portfolio of 16 Prescription Drugs Merger/Acquisition Biophausia AB 535 535
- Chugai Pharmaceutical Co. Ltd. Merger/Acquisition Roche Holding AG 95,029 837,938
- ISIS Pharmaceuticals Inc. Shelf Registration - - -
5/21/2008 SkyePharma plc Buyback - - -
5/19/2008 Baxter International Inc. Public Offering - - -
- Harvard Bioscience Inc. Shelf Registration - - -
- Vertex Pharmaceuticals Inc. Shelf Registration - - -
- Vertex Pharmaceuticals Inc. Shelf Registration - - -
- Myriad Genetics Inc. Shelf Registration - - -
- Wyeth Shelf Registration - - -
- Wyeth Shelf Registration - - -
4/24/2008 AstraZeneca plc Buyback - - -
4/22/2008 Cangene Corp. Buyback - - -
4/20/2008 Amgen Inc. Public Offering - - -
4/20/2008 Amgen Inc. Public Offering - - -
- Affymax, Inc. Shelf Registration - - -
- Amgen Inc. Shelf Registration - - -
4/16/2008 AVANT Immunotherapeutics, Inc., Exclusive Worldwide License to CDX-110 Merger/Acquisition Pfizer Inc. 430 430
4/22/2008 Sirtris Pharmaceuticals, Inc. Merger/Acquisition SmithKline Beecham Corporation 727 620
4/7/2008 Washington Mutual Inc. Private Placement ACE European Group; ACE Property and Casualty Insurance Company; AIG SunAmerica Asset Management Corp.; Alberta Teachers' Retirement Fund Board; AllianceBernstein L.P.; AllianceBernstein Tax-Managed Balanced Wealth Strategy; AllianceBernstein Tax-Managed Wealth Appreciation Strategy; AllianceBernstein Tax-Managed Wealth Preservation Strategy; AllianceBernstein Value Fund; American Airlines Master Fixed Benefit Pension Plan Trust; American Beacon Balanced Fund; American Beacon Funds - Large Cap Value Fund; American Funds Insurance Series - Blue Chip Income and Growth Fund; American Funds Insurance Series - Growth-Income Fund; American Hospital Association Inc; American University Endowment, The; Asstel Lebensversicherung AG; AST Investment Services, Inc.; AST Large-Cap Value Portfolio; AST T. Rowe Price Asset Allocation Portfolio; Austin Presbyterian Theological Seminary Inc; AustralianSuper Pty Ltd; Avon Products Inc.; AXA Premier VIP Trust - Multimanager Large Cap Value Portfolio; Baltimore City Fire and Police Employees’ Retirement System; Barrow, Hanley, Mewhinney & Strauss, Inc.; Bay Pond Investors Bermuda L.P; Bay Pond Partners, L.P; Boeing Co., Pension Arm; Brandes Canada Global Equity Unit Trust; Brandes Global Balanced Fund; Brandes Global Equity Fund (Can); Brandes Investment Funds PLC-Brandes U.S. Equities Fund; Brandes Investment Partners & Co.; Brandes Investment Partners, L.P.; Brandes U.S. Equity Fund (Can); Brandywine Global Investment Management, LLC; Brisbane City Council; Building Trades United Pension Trust Fund; California Pacific Medical Center; California State Automobile Association, Pension Arm; Canadian Medical Association; Capital Research and Management Company; Cif All Cap Equity Fund; City Of Winston-Salem; Claymore Securities, Inc.; Co-operative Superannuation Society Pension Plan; Colleges of Applied Arts and Technology Pension Plan; Columbia Global Value Fund; Communities Foundation of Texas; Conocophillips Retirement Plan; Consolidated Rail Corporation; Conventum Asset Management S.A.; Core Allocation Plus Trust; Counsel Group of Funds, Inc.; Counsel Select America (Can); Counsel World Managed Portfolio; D. E. Shaw Investment Management, L.L.C.; D. E. Shaw Oculus Portfolios, L.L.C.; D.E. Shaw Valence Portfolios LLC; Derbyshire County Council; Desjardins Asset Management; Desjardins Global Asset Management Inc.; Deutsche Investment Management Americas Inc.; DG Capital Management, Inc.; DGAM U.S. Equity Fund L.P.; Diversified Investment Advisors, Inc.; Doris Duke Foundation, Endowment; Dow Chemical Co, Pension Arm; Dow Employees Pension Plan; Dreman Contrarian Large Cap Value Fund; Dreman Value Management, L.L.C.; Dreman/Claymore Dividend & Income Fund; DWS Dreman Concentrated Value Fund; DWS Dreman High Return Equity Fund; DWS Dreman High Return Equity VIP; DWS Dreman Value Income Edge Fund, Inc.; EARNEST Partners, LLC; Electronic Data Systems Corporation; Emerson Electric Co.; Energy Future Holdings Corporation; Engineering Industries Pension Fund; EQ/Mutual Shares; Equipsuper Superannuation Fund; Erie Indemnity Co.; Erie Insurance Exchange; Evangelical Lutheran Church in America Board of Pensions; Exel plc; Farallon Capital Institutional Partners II, L.P.; Farallon Capital Institutional Partners III, L.P.; Farallon Capital Institutional Partners, L.P.; Farallon Capital Management, L.L.C.; Farallon Capital Offshore Investors II, L.P; Farallon Capital Partners, L.P.; Fidelity Advisor Balanced Fund; Fidelity Advisor Dividend Growth Fund; Fidelity Advisor Financial Services Fund; Fidelity Advisor High Income Advantage Fund; Fidelity Advisor Large Cap Fund; Fidelity Advisor Leveraged Company Stock Fund; Fidelity Advisor Series I - Fidelity Advisor Value Strategies Fund; Fidelity Advisor Series VIII - Fidelity Advisor Global Capital Appreciation Fund; Fidelity Advisor Value Leaders Fund; Fidelity Central Investment Portfolios LLC - Fidelity Financials Central Fund; Fidelity Commonwealth Trust - Fid - -
- OSI Pharmaceuticals Inc. Shelf Registration - - -
3/18/2008 Baxter International Inc. Buyback - - -
- Affymax, Inc. Shelf Registration - - -
- Affymax, Inc. Shelf Registration - - -
- Acorda Therapeutics, Inc. Shelf Registration - - -
3/12/2008 Novo Nordisk A/S Buyback - - -
- Altus Pharmaceuticals Inc. Shelf Registration - - -
- Celgene Corporation Shelf Registration - - -
3/6/2008 Akzo Nobel NV Buyback - - -
3/6/2008 Biovator AB Private Placement ALMI Företagspartner Stockholm AB; AstraZeneca plc; IBL Gesellschaft für Immunchemie und Immunbiologie mbH; LinkMed AB; Linköpings universitet; Medicago Inc. - -
3/3/2008 Serenex, Inc. Merger/Acquisition Pfizer Inc. - -
2/26/2008 Biogen Idec Inc. Public Offering - - -
2/26/2008 Biogen Idec Inc. Public Offering - - -
- Biogen Idec Inc. Shelf Registration - - -
2/21/2008 Imaginatik PLC Private Placement Pfizer Inc. - -
2/20/2008 Encysive Pharmaceuticals Inc. Merger/Acquisition Pfizer Inc. 380 347
2/20/2008 Acceleron Pharma, Inc. Private Placement Celgene Corporation - -
2/15/2008 Q Therapeutics, Inc. Private Placement EPIC Ventures; Invitrogen Corp.; Salt Lake Life Science Angels, Investment Arm; Toucan Capital Corp.; Toucan Capital Fund II, L.P.; University Of Utah Research Foundation; vSpring Capital - -
- Polynt S.p.A. Merger/Acquisition InvestIndustrial Holdings Limited 347 437
- Vertex Pharmaceuticals Inc. Shelf Registration - - -
2/11/2008 Vertex Pharmaceuticals Inc. Public Offering - - -
2/11/2008 Vertex Pharmaceuticals Inc. Public Offering - - -
- Vertex Pharmaceuticals Inc. Shelf Registration - - -
2/6/2008 Acorda Therapeutics, Inc. Public Offering - - -
- Acorda Therapeutics, Inc. Shelf Registration - - -
2/1/2008 Neurorecovery, Inc., Aminopyridine and Pre-Clinical Assets Merger/Acquisition Acorda Therapeutics, Inc. 3 3
2/1/2008 Amgen Kabushiki Kaisha Merger/Acquisition Takeda Pharmaceutical Co. Ltd. - -
1/23/2008 Pfizer Inc. Buyback - - -
1/22/2008 Celgene Corporation Public Offering - - -
1/18/2008 Pfizer Inc., Manufacturing Facility in Italy Merger/Acquisition Actavis Group Hf. - -
1/15/2008 Aerogen Inc. Merger/Acquisition - - -
1/10/2008 CellzDirect, Inc. Merger/Acquisition Invitrogen Corp. 57 57
1/8/2008 Biogen Idec Inc., PDL BioPharma, Inc., Licensing for Volociximab (M200) Merger/Acquisition Ophthotech Corporation - -
1/8/2008 Amgen Inc., Worldwide Rights Of AMG 623 Merger/Acquisition Anthera Pharmaceuticals, Inc. - -
1/7/2008 Isis Pharmaceuticals, Inc., Exclusive Worldwide License Of Mipomersen Merger/Acquisition Genzyme Corp. 1,750 1,750
1/7/2008 ISIS Pharmaceuticals Inc. Private Placement Genzyme Corp. - -
1/4/2008 OSI Pharmaceuticals Inc. Buyback - - -
- Cubist Pharmaceuticals Inc. Shelf Registration - - -
- Cubist Pharmaceuticals Inc. Shelf Registration - - -
1/3/2008 OSI Pharmaceuticals Inc. Private Placement - - -
12/31/2007 Heumann PCS GmbH Merger/Acquisition Fareva SA - -
12/27/2007 Polynt S.p.A. Merger/Acquisition InvestIndustrial Holdings Limited 105 446
12/24/2007 Illumigen Biosciences, Inc. Merger/Acquisition Cubist Pharmaceuticals Inc. 358 357
12/21/2007 Hennecke Gmbh Merger/Acquisition Meyer Burger Technology AG 14 20
- OSI Pharmaceuticals Inc. Shelf Registration - - -
12/18/2007 CovX Research LLC Merger/Acquisition Pfizer Inc. - -
12/15/2007 USB Corporation Merger/Acquisition Affymetrix Inc. 75 75
12/14/2007 TcLand SA Private Placement Auriga Partners; Beviguen; Debioinnovation; Genzyme Corp.; Quest for Growth NV; Quest Management NV - -
12/12/2007 Lonza Group AG Merger/Acquisition - 548 8,270
- Harvard Bioscience Inc. Merger/Acquisition Skystone Capital Management, L.P. 133 143
12/6/2007 Pfizer Inc. Public Offering - - -
12/6/2007 Caris MPI Merger/Acquisition Caris Diagnostics, Inc. 40 40
12/6/2007 Harvard Bioscience Inc. Buyback - - -
12/4/2007 Baxter International Inc. Public Offering - - -
11/30/2007 Genomic Solutions Division and Maia Scientific Merger/Acquisition Digilab, Inc. 1 1
11/28/2007 Regeneron Pharmaceuticals Inc. Private Placement Sanofi-Aventis - -
11/27/2007 Xenome Limited Private Placement Amylin Pharmaceuticals Inc.; Queensland BioCapital Fund; Queensland BioCapital Funds Pty Ltd. - -
11/16/2007 Amgen Inc. Public Offering - - -
11/15/2007 Coley Pharmaceutical Group, Inc. Merger/Acquisition Pfizer Inc. 230 143
- Cephalon Inc. Shelf Registration - - -
11/13/2007 Affymetrix Inc. Public Offering - - -
- Affymetrix Inc. Shelf Registration - - -
- Vertex Pharmaceuticals Inc. Shelf Registration - - -
- Acorda Therapeutics, Inc. Shelf Registration - - -
10/30/2007 Hennecke Gmbh Merger/Acquisition ADCURAM Industriekapital AG - -
10/22/2007 Gilead Sciences Inc. Buyback - - -
10/16/2007 Kaketsu Ken, K.k., ADAMTS13 Merger/Acquisition Baxter International Inc. - -
10/11/2007 Panlab, S.L. Merger/Acquisition Harvard Bioscience Inc. 5 5
10/11/2007 Nobilas International B.V. Merger/Acquisition Innovation Group plc 1 1
- Imclone Systems Inc. Shelf Registration - - -
10/9/2007 NPS Pharmaceuticals, Inc., Assets Related To mGluR Collaboration Merger/Acquisition AstraZeneca plc 30 30
10/8/2007 QLT Plug Delivery, Inc. Merger/Acquisition QLT Inc. 101 101
9/27/2007 Lonza Singapore Pte. Ltd. Merger/Acquisition Perstorp AB 138 138
- Alexion Pharmaceuticals, Inc. Shelf Registration - - -
9/26/2007 GlobeImmune, Inc. Private Placement Adams Street Partners, LLC; Biogen Idec New Ventures; Boston Life Science Venture Corp.; Celgene Corporation; China Investment & Development Co. Ltd.; Eminent Venture Capital Corp.; G C & H Investments; HealthCare Ventures LLC; Lilly Ventures; Medica Venture Partners; Mellon Family Investment Co. Vi; Morgenthaler; Pac-Link Management Corp.; Partners Healthcare System, Inc.; Richard King Mellon Foundation, Endowment Fund; Sequel Venture Partners; Wexford Capital LLC; WRF Capital; Yasuda Enterprise Development 1 L.P. - -
9/13/2007 PTC Therapeutics, Inc. Private Placement Celgene Corporation - -
9/11/2007 Biotest Pharmaceuticals Corporation Merger/Acquisition Biotest AG 185 185
9/5/2007 Kelaroo, Inc. Private Placement Amylin Pharmaceuticals Inc. - -
8/31/2007 AstraZeneca plc Public Offering - - -
- AstraZeneca plc Shelf Registration - - -
8/30/2007 American Medical Instruments Holdings, Inc. Merger/Acquisition - 2 2
11/18/2007 Pharmion Corp. Merger/Acquisition Celgene Corporation 2,721 2,603
8/23/2007 ECR Pharmaceuticals, Amrix Merger/Acquisition Cephalon Inc. 100 100
8/22/2007 CSL Ltd. Buyback - - -
8/20/2007 Encysive Pharmaceuticals Inc. Private Placement Enable Capital Management; Enable Growth Partners, LP; Enable Opportunity Partners LP; Hudson Bay Capital Management LP; Hudson Bay Fund LP; Hudson Bay Overseas Fund Ltd; Pierce Diversified Strategy Master Fund, LLC - -
- Imperial Chemical Industries plc Merger/Acquisition Akzo Nobel NV 9,164 7,866
- Amylin Pharmaceuticals Inc. Shelf Registration - - -
8/7/2007 Grifols, S.A. Merger/Acquisition FIL Limited. - -
8/1/2007 Invitrogen Corp. Buyback - - -